U.S. SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549

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FORM 4                                                      OMB APPROVAL
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[_] Check this box if no longer                    OMB NUMBER          3235-0287
    subject to Section 16. Form 4                  Expires:   September 30, 1998
    or Form 5 obligations may                      Estimated average burden
    continue. SEE Instruction 1(b).                hours per response ...... 0.5
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                 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

    Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934,
      Section 17(a) of the Public Utility Holding Company Act of 1935 or
              Section 30(f) of the Investment Company Act of 1940


1. Name and Address of Reporting Person*

   Syal                               Madan
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  (Last)                             (First)                         (Middle)

                             c/o OSI Systems, Inc.
                             12525 Chadron Avenue
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                                    (Street)

Hawthorne                              Ca.                            90250
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  (City)                             (State)                          (Zip)


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2. Issuer Name and Ticker or Trading Symbol

                           OSI Systems, Inc. (OSIS)
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3. IRS or Social Security Number of Reporting Person (Voluntary)


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4. Statement for Month/Year

                                     10/01
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5. If Amendment, Date of Original   (Month/Year)


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6. Relationship of Reporting Person to Issuer
       (Check all applicable)


           [X]  Director                    [_]  10% Owner

           [_]  Officer (give title below)  [_]  Other (Specify below)


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7. Individual or Joint/Group Filing (Check applicable line)
   [X] Form filed by One Reporting Person
   [_] Form filed by More than One Reporting Person
Table 1 -- Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1. Title of Security 2. Trans- 3. Trans- 4. Securities Acquired (A) 5. Amount of 6. Ownership 7. Nature (Instr. 3) action action or Disposed of (D) Securities Form: of Indirect Date Code Beneficially Direct Beneficial (Instr. 8) (Instr. 3,4 and 5) Owned at (D) or Ownership (Month/ ------------ -------------------------- End of Month Indirect (Instr. 4) Day/ Code V Amount (A) or Price (Instr. 3 (I) Year) (D) and 4) (Instr. 4) -------------------------- ---------- ------ ---- -------- ------ ------ -------------- ------------ ------------- Common Stock 9/21/01 S 10,054 D $8.20 85,625 I By Syal Trust -------------------------- ---------- ------ ---- -------- ------ ------ -------------- ------------ ------------- -------------------------- ---------- ------ ---- -------- ------ ------ -------------- ------------ -------------
* If the Form is filed by more than one Reporting Person, see Instruction 4(b)(v). Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. (Print or Type Responses) (Over) SEC 1473 (8-92) FORM 4 (continued)
1. Title of Derivative Security 2. Conversion 3. Transaction 4. Transacation 5. Number of Derivative 6. Date Exercisable (Instr. 3) or Exercise Date Code Securities Acquired (A) and Expiration Price of (Instr. 8) or Disposed (D) of Date Derivative (Month/Day/ (Instr. 3, 4, and 5) (Month/Day/ Security Year) Year) --------------- -------------------------- ------------------- Code V (A) (D) Date Expiration Exer- Date cisable ------------------------------- -------------- -------------- -------- ----- --------------- ---------- -------- ---------- ------------------------------- -------------- -------------- -------- ----- --------------- ---------- -------- ---------- ------------------------------- -------------- -------------- -------- ----- --------------- ---------- -------- ---------- ------------------------------- -------------- -------------- -------- ----- --------------- ---------- -------- ---------- ------------------------------- -------------- -------------- -------- ----- --------------- ---------- -------- ---------- ------------------------------- -------------- -------------- -------- ----- --------------- ---------- -------- ---------- ------------------------------- -------------- -------------- -------- ----- --------------- ---------- -------- ---------- ------------------------------- -------------- -------------- -------- ----- --------------- ---------- -------- ---------- ------------------------------- -------------- -------------- -------- ----- --------------- ---------- -------- ----------
7. Title and Amount of 8. Price of Derivative 9. Number of Derivative 10. Ownership Form 11. Nature of Indirect Underlying Securities Security Securities Beneficially of Derivative Security: Beneficial Ownership Owned at End of Month Direct (D) or (Instr. 3 and 4) (Instr. 5) Indirect (I) (Instr. 4) ------------------------ (Instr. 4) Title Amount or (Instr. 4) Number of Shares ------------------------ ---------------------- -------------------------- --------------------------- ------------------------ ------------------------ ---------------------- -------------------------- --------------------------- ------------------------ ------------------------ ---------------------- -------------------------- --------------------------- ------------------------ ------------------------ ---------------------- -------------------------- --------------------------- ------------------------ ------------------------ ---------------------- -------------------------- --------------------------- ------------------------ ------------------------ ---------------------- -------------------------- --------------------------- ------------------------ ------------------------ ---------------------- -------------------------- --------------------------- ------------------------ ------------------------ ---------------------- -------------------------- --------------------------- ------------------------ ------------------------ ---------------------- -------------------------- --------------------------- ------------------------
Explanation of Responses: **Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). /s/ Madan Syal 10/05/01 _______________________________ ______________ **Signature of Reporting Person Date Note: File three copies of this Form, one of which must be manually signed. If space provided is insufficient, See Instruction 6 for procedure. Page 2